Mission: Provide comprehensive flight safety management to the Air Force and acquisition community through a safety management system using risk mitigation and analysis.

Aviation Safety ​is required for each unit conducting or supporting flight operations, to include small unmanned aircraft systems operations. There are several programs that fall under the SEF's responsibility. These are:

• Bird/Wildlife Aircraft Strike Hazard (BASH) activities
• Hazardous Air Traffic Reporting (HATR) Program
• High Accident Potentials (HAPs)
• Midair Collision Avoidance (MACA) Program
• Awards Program recognition
• Data-centric Proactive Safety Programs

Mission: Ensure effective safety hazard and risk management in acquisition programs by building, delivering, and sustaining the system safety engineering and management disciplines; enhancing operational suitability, safety and effectiveness while reducing mishaps, thus promoting success of the USAF mission with lowest possible safety risk.

The application of engineering and management principles, criteria, and techniques to achieve acceptable risk within the constraints of operational effectiveness and suitability, time and cost throughout all phases of the system life-cycle.

Mission: Provide superior Occupational Safety while protecting Air Force personnel from death, injuries or occupational illnesses by managing risk on- and off-duty.  Primary areas of responsibility include:

• Workplace hazards
• Occupational Safety
• Occupational Safety and Health Administration (OSHA) Support
• On-base sports
• Motorcycle Safety Program
• Review Civil Engineering activities​
• AF Supervisor Safety Training (SST)
• Unit Safety Representative (USR) Program
• Hazard Identification and Abatement

Mission: Provides strategic guidance and practical implementation of test safety for Program Offices executing test and evaluation, developmental and operational, under the Alternate Lead Developmental Test Organization construct.  Ensures Program Offices with Prime Contractor executing T&E conform to, and execute in accordance with, current Air Force directives, guidance, and policy. Integrates System Safety hazard assessments with test operational execution to provide the testing organization independent and objective governmental safety review of the test program and plan.

Independent government technical, environment, and safety personnel examine the technical, environment, and safety aspects of T&E plans that involve government resources prior to commencement of test activities. 

Mission: Provide world-class weapons safety expertise to the US Air Force and Defense Contractors supporting the war fighter and the acquisition community.

The Weapons Safety program comprises four disciplines:

• Explosives Safety
• Missile Safety
• Nuclear Surety
• Directed Energy Weapon (DEW) Safety​